Motif ID: FOX{F1,F2,J1}.p2

Z-value: 0.166


Transcription factors associated with FOX{F1,F2,J1}.p2:

Gene SymbolEntrez IDGene Name
FOXF1 2294 forkhead box F1
FOXF2 2295 forkhead box F2
FOXJ1 2302 forkhead box J1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXJ1hg19_v1_chr17_-_74137370_74137379-0.373.5e-02Click!
FOXF2hg19_v1_chr6_+_1390068_1390182-0.222.3e-01Click!
FOXF1hg19_v1_chr16_+_86544104_865442080.048.3e-01Click!


Activity profile for motif FOX{F1,F2,J1}.p2.

activity profile for motif FOX{F1,F2,J1}.p2


Sorted Z-values histogram for motif FOX{F1,F2,J1}.p2

Sorted Z-values for motif FOX{F1,F2,J1}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{F1,F2,J1}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_161193190 7.709 APOA2
apolipoprotein A-II
chr1_+_207277577 7.200 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr1_-_161193375 6.990 NM_001643
APOA2
apolipoprotein A-II
chr4_+_155484131 6.821 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr22_+_21128378 5.489 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr1_-_57431620 4.762 NM_000066
C8B
complement component 8, beta polypeptide
chr11_+_124789145 4.762 NM_001037558
HEPN1
hepatocellular carcinoma, down-regulated 1
chr12_-_96390002 4.167 NM_002108
HAL
histidine ammonia-lyase
chr4_+_74269971 4.166 NM_000477
ALB
albumin
chr1_+_40862471 3.800 NM_001198980
SMAP2
small ArfGAP2
chr8_+_120079423 3.754 NM_006438
COLEC10
collectin sub-family member 10 (C-type lectin)
chr4_-_72671236 3.314 NM_001204306
GC
group-specific component (vitamin D binding protein)
chr17_-_7082559 3.295 ASGR1
asialoglycoprotein receptor 1
chr17_-_26697358 3.259 NM_000638
VTN
vitronectin
chr17_-_7082654 3.214 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr2_-_21230572 3.186 APOB
apolipoprotein B (including Ag(x) antigen)
chr17_-_26697224 3.155 VTN
vitronectin
chr17_-_26697310 3.027 VTN
vitronectin
chr2_-_21231406 2.982 APOB
apolipoprotein B (including Ag(x) antigen)
chr17_-_26697293 2.922 VTN
vitronectin
chr1_+_192544856 2.848 NM_002922
RGS1
regulator of G-protein signaling 1
chr1_-_169555624 2.847 F5
coagulation factor V (proaccelerin, labile factor)
chr6_-_128239741 2.791 NM_001164687
THEMIS
thymocyte selection associated
chr3_-_10547340 2.767 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr4_+_74270832 2.737 ALB
albumin
chr4_-_176734181 2.641 NM_201591
GPM6A
glycoprotein M6A
chr12_+_20963637 2.485 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr4_-_72669757 2.322 NM_001204307
GC
group-specific component (vitamin D binding protein)
chr16_+_27341305 2.211 IL4R
interleukin 4 receptor
chr5_+_166711842 2.199 NM_001122679
ODZ2
odz, odd Oz/ten-m homolog 2 (Drosophila)
chr2_-_233877920 2.194 NM_019850
NGEF
neuronal guanine nucleotide exchange factor
chr12_+_79258588 2.091 SYT1
synaptotagmin I
chr13_-_103054027 2.070 NM_175929
FGF14
fibroblast growth factor 14
chr2_+_162272619 2.067 NM_006593
TBR1
T-box, brain, 1
chr4_+_100495972 2.006 MTTP
microsomal triglyceride transfer protein
chr4_-_155511838 2.004 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr1_-_197036350 1.989 NM_001994
F13B
coagulation factor XIII, B polypeptide
chr3_-_10547267 1.978 NM_001001331
NM_001683
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr2_+_33661392 1.938 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_-_219031646 1.920 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr1_-_169555710 1.911 NM_000130
F5
coagulation factor V (proaccelerin, labile factor)
chr4_-_70361578 1.907 NM_021139
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
chr2_-_233877901 1.902 NGEF
neuronal guanine nucleotide exchange factor
chr13_-_45775174 1.863 NM_198404
KCTD4
potassium channel tetramerisation domain containing 4
chr17_-_5138049 1.854 NM_207103
SCIMP
SLP adaptor and CSK interacting membrane protein
chr19_-_58864820 1.814 NM_130786
A1BG
alpha-1-B glycoprotein
chr19_-_52255099 1.812 NM_001193306
NM_002029
FPR1

formyl peptide receptor 1

chr9_-_116840545 1.806 AMBP
alpha-1-microglobulin/bikunin precursor
chr17_+_72733350 1.801 NM_001006638
NM_001163990
RAB37

RAB37, member RAS oncogene family

chr14_+_95078713 1.795 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr6_-_138820578 1.765 NM_001144060
NHSL1
NHS-like 1
chr17_+_9745847 1.724 GLP2R
glucagon-like peptide 2 receptor
chr6_-_25930838 1.702 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr19_-_48389514 1.696 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr12_-_21487831 1.694 NM_021094
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr5_-_42811959 1.689 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr15_-_40600025 1.681 PLCB2
phospholipase C, beta 2
chr16_+_56225301 1.656 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr9_-_116840460 1.644 AMBP
alpha-1-microglobulin/bikunin precursor
chr14_+_88471467 1.629 NM_003608
GPR65
G protein-coupled receptor 65
chr17_-_29641087 1.615 EVI2B
ecotropic viral integration site 2B
chr15_-_40600118 1.611 NM_004573
PLCB2
phospholipase C, beta 2
chr4_+_187187342 1.596 F11
coagulation factor XI
chr4_-_39033981 1.586 NM_024943
TMEM156
transmembrane protein 156
chr7_-_126883568 1.554 NM_000845
GRM8
glutamate receptor, metabotropic 8
chr2_-_216246961 1.520 FN1
fibronectin 1
chr7_-_87342569 1.520 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr6_+_44244465 1.519 TMEM151B
transmembrane protein 151B
chr15_-_40599872 1.512 PLCB2
phospholipase C, beta 2
chr14_+_100563817 1.491 EVL
Enah/Vasp-like
chr5_-_83016850 1.484 NM_001884
HAPLN1
hyaluronan and proteoglycan link protein 1
chr17_-_29641094 1.478 NM_006495
EVI2B
ecotropic viral integration site 2B
chr5_-_142065991 1.476 NM_033136
FGF1
fibroblast growth factor 1 (acidic)
chr5_-_36301999 1.472 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr3_+_98451537 1.466 NM_006100
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr10_-_54531394 1.429 NM_000242
MBL2
mannose-binding lectin (protein C) 2, soluble
chr14_-_74551159 1.428 NM_005589
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr10_-_52645384 1.422 A1CF
APOBEC1 complementation factor
chr2_-_44065888 1.411 NM_022436
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr3_+_114012832 1.405 NM_173799
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr9_-_116840551 1.397 AMBP
alpha-1-microglobulin/bikunin precursor
chr3_-_165555167 1.391 BCHE
butyrylcholinesterase
chr5_-_142065586 1.389 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chr2_-_216249682 1.383 FN1
fibronectin 1
chr4_-_88243994 1.382 NM_001136230
NM_178135
HSD17B13

hydroxysteroid (17-beta) dehydrogenase 13

chr3_-_165555252 1.381 NM_000055
BCHE
butyrylcholinesterase
chr14_-_70263871 1.379 NM_003049
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr16_-_86542463 1.370 LOC400550
uncharacterized LOC400550
chr19_+_15751706 1.346 NM_000896
NM_001199208
NM_001199209
CYP4F3


cytochrome P450, family 4, subfamily F, polypeptide 3


chr5_-_132161863 1.340 NM_133456
SHROOM1
shroom family member 1
chr14_-_94789641 1.337 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr4_+_187187117 1.336 NM_000128
F11
coagulation factor XI
chr1_-_240775448 1.333 NM_022469
GREM2
gremlin 2
chr18_+_55019720 1.332 NM_015879
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr14_-_74551073 1.303 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr9_-_19786886 1.293 NM_001193288
NM_020344
SLC24A2

solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

chr8_+_1952875 1.287 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr6_-_138820580 1.280


chr2_+_210444154 1.279 MAP2
microtubule-associated protein 2
chr17_-_29641068 1.275 EVI2B
ecotropic viral integration site 2B
chr12_-_103310896 1.266 PAH
phenylalanine hydroxylase
chr1_+_198608244 1.265 PTPRC
protein tyrosine phosphatase, receptor type, C
chr13_-_61989209 1.263 PCDH20
protocadherin 20
chr5_+_60933635 1.243 NM_173667
C5orf64
chromosome 5 open reading frame 64
chr2_+_219646448 1.228 NM_000784
CYP27A1
cytochrome P450, family 27, subfamily A, polypeptide 1
chr5_+_161275897 1.219 NM_001127646
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chrX_-_65259839 1.197 NM_001100431
NM_001184830
NM_001184831
NM_007268
VSIG4



V-set and immunoglobulin domain containing 4



chr22_-_37505602 1.150 TMPRSS6
transmembrane protease, serine 6
chr13_-_46756326 1.139 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr15_+_58430394 1.129 NM_020980
AQP9
aquaporin 9
chr10_+_70847817 1.128 NM_002727
SRGN
serglycin
chr12_-_11548485 1.118 NM_006248
PRB1
PRB2
proline-rich protein BstNI subfamily 1
proline-rich protein BstNI subfamily 2
chr22_+_41074994 1.112 NM_005297
MCHR1
melanin-concentrating hormone receptor 1
chr8_-_26724728 1.103


chr6_-_159466019 1.100 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr17_+_8924822 1.098 NM_004822
NTN1
netrin 1
chr10_-_91405320 1.092 NM_148977
PANK1
pantothenate kinase 1
chr9_+_136287119 1.083 NM_139025
NM_139026
NM_139027
ADAMTS13


ADAM metallopeptidase with thrombospondin type 1 motif, 13


chr21_-_35899046 1.082 NM_203418
RCAN1
regulator of calcineurin 1
chr2_-_40657419 1.074 NM_001112800
NM_001112801
NM_001252624
NM_021097
SLC8A1



solute carrier family 8 (sodium/calcium exchanger), member 1



chr2_+_89185055 1.073


chr2_+_173686314 1.071 NM_001100397
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr1_-_230850335 1.067 NM_000029
AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr17_-_7017971 1.065 ASGR2
asialoglycoprotein receptor 2
chr8_-_110655418 1.058 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr13_-_46756291 1.050 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_-_216242916 1.047 FN1
fibronectin 1
chr7_-_14025826 1.040 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr10_+_7745341 1.037 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr14_-_106478129 1.036 IGHV4-31
IGHD
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr2_+_44066102 1.036 NM_022437
ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8
chr19_+_1207129 1.032 EFNA2
ephrin-A2
chr3_+_108855560 1.028 FLJ22763
uncharacterized LOC401081
chrX_+_78426468 1.015 NM_032553
GPR174
G protein-coupled receptor 174
chr3_-_183273407 1.015 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr4_+_88754120 1.012 NM_001184695
NM_001184696
NM_001184697
NM_020203
MEPE



matrix extracellular phosphoglycoprotein



chr20_-_1309782 0.990 SDCBP2
syndecan binding protein (syntenin) 2
chr22_+_37309618 0.988 NM_000395
CSF2RB
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chrX_+_46940235 0.984 RGN
regucalcin (senescence marker protein-30)
chr14_+_23845932 0.978 NM_001037288
NM_138460
CMTM5

CKLF-like MARVEL transmembrane domain containing 5

chr8_+_67344717 0.969 NM_144650
ADHFE1
alcohol dehydrogenase, iron containing, 1
chr1_-_240775388 0.969 GREM2
gremlin 2
chr3_+_158991090 0.968 SCHIP1
schwannomin interacting protein 1
chr7_+_50348255 0.967 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr7_+_136553398 0.958 NM_001006627
NM_001006630
CHRM2

cholinergic receptor, muscarinic 2

chr10_+_70847857 0.957 SRGN
serglycin
chr10_+_7745325 0.957 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr5_-_36241684 0.948 NADKD1
NAD kinase domain containing 1
chr2_+_143635225 0.940 KYNU
kynureninase
chr1_+_241695433 0.937 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr2_+_143635194 0.937 NM_001032998
NM_001199241
NM_003937
KYNU


kynureninase


chr12_+_121570630 0.936 NM_002562
P2RX7
purinergic receptor P2X, ligand-gated ion channel, 7
chr10_-_52645430 0.934 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr4_-_82393025 0.933 NM_152545
RASGEF1B
RasGEF domain family, member 1B
chr8_-_133459508 0.929 NM_001204824
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr12_+_123319293 0.927 HIP1R
huntingtin interacting protein 1 related
chr18_-_24765178 0.927 NM_031422
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr1_+_65730423 0.922 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr4_-_111119752 0.921 NM_001130721
NM_024090
ELOVL6

ELOVL fatty acid elongase 6

chr14_-_21493122 0.917 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr9_-_116840604 0.915 AMBP
alpha-1-microglobulin/bikunin precursor
chrX_+_38211735 0.915 NM_000531
OTC
ornithine carbamoyltransferase
chr14_-_106829736 0.914 IGHA1
IGHD
IGHG3
IGHM
SKAP2
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
src kinase associated phosphoprotein 2
chr17_+_26662547 0.909 NM_021137
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr1_-_47695442 0.903 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr11_-_116708334 0.901 NM_000039
APOA1
apolipoprotein A-I
chr10_+_92922696 0.901 PCGF5
polycomb group ring finger 5
chr1_-_93342706 0.892 NM_001252271
FAM69A
family with sequence similarity 69, member A
chr22_+_23054862 0.886 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr4_+_39063851 0.864 NM_015990
NM_199039
KLHL5

kelch-like 5 (Drosophila)

chr15_-_22473092 0.862


chr6_+_31895201 0.859 NM_000063
NM_001145903
C2

complement component 2

chr4_+_172734574 0.859 NM_001034845
GALNTL6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr10_+_96522457 0.852 NM_000769
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr20_-_22566092 0.851 NM_153675
FOXA2
forkhead box A2
chrX_-_19688991 0.849 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr12_-_11508509 0.840 NM_005039
NM_199353
NM_199354
PRB1


proline-rich protein BstNI subfamily 1


chr20_+_42193754 0.840 NM_001199264
SGK2
serum/glucocorticoid regulated kinase 2
chr5_-_169724614 0.835 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr16_+_30483959 0.831 NM_001114380
NM_002209
ITGAL

integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)

chr3_+_108541544 0.827 NM_016388
TRAT1
T cell receptor associated transmembrane adaptor 1
chr6_-_56716713 0.821 DST
dystonin
chr4_+_39408472 0.819 NM_175737
KLB
klotho beta
chr1_+_198608216 0.816 PTPRC
protein tyrosine phosphatase, receptor type, C
chr1_-_246729439 0.812 TFB2M
transcription factor B2, mitochondrial
chr7_-_99381703 0.810 NM_001202855
NM_017460
CYP3A4

cytochrome P450, family 3, subfamily A, polypeptide 4

chr19_-_33360641 0.810 NM_001126335
NM_001243036
NM_014270
SLC7A9


solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9


chr1_+_200011716 0.809 NR5A2
nuclear receptor subfamily 5, group A, member 2
chr17_+_72732958 0.806 NM_001163989
RAB37
RAB37, member RAS oncogene family
chr12_+_79439432 0.803 NM_001135806
SYT1
synaptotagmin I
chr1_-_186649421 0.801 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr21_+_34602304 0.794 IFNAR2
interferon (alpha, beta and omega) receptor 2
chr5_-_36241899 0.792 NM_001085411
NADKD1
NAD kinase domain containing 1
chr12_-_63328857 0.791 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr12_-_10573041 0.786 NM_002261
NM_007333
KLRC3

killer cell lectin-like receptor subfamily C, member 3

chr12_-_9913415 0.786 NM_001781
CD69
CD69 molecule
chr9_+_136287443 0.786 ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr11_-_118084073 0.777 NM_153206
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr4_-_70626429 0.776 NM_014465
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr9_+_120466453 0.772 NM_138554
TLR4
toll-like receptor 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.93 1.20e-07 GO:0050896 response to stimulus
26.86 5.84e-05 GO:0008206 bile acid metabolic process
7.86 1.06e-04 GO:0051241 negative regulation of multicellular organismal process
7.57 5.70e-04 GO:0008202 steroid metabolic process
3.58 7.83e-04 GO:0032879 regulation of localization
3.67 1.10e-03 GO:0009611 response to wounding
16.29 1.24e-03 GO:0010951 negative regulation of endopeptidase activity
2.49 1.51e-03 GO:0065008 regulation of biological quality
41.40 1.52e-03 GO:0015721 bile acid and bile salt transport
4.80 2.08e-03 GO:0007596 blood coagulation
4.80 2.08e-03 GO:0050817 coagulation
4.77 2.24e-03 GO:0007599 hemostasis
4.74 2.41e-03 GO:0001775 cell activation
3.47 2.43e-03 GO:0006629 lipid metabolic process
82.79 2.98e-03 GO:0030300 regulation of intestinal cholesterol absorption
13.25 4.20e-03 GO:0002576 platelet degranulation
6.78 5.10e-03 GO:0030168 platelet activation
3.82 5.68e-03 GO:0051049 regulation of transport
1.52 5.90e-03 GO:0065007 biological regulation
9.14 8.20e-03 GO:0051346 negative regulation of hydrolase activity
62.09 8.26e-03 GO:0032372 negative regulation of sterol transport
62.09 8.26e-03 GO:0032375 negative regulation of cholesterol transport
4.18 9.33e-03 GO:0050878 regulation of body fluid levels
4.03 1.37e-02 GO:0042060 wound healing
10.81 1.37e-02 GO:0010466 negative regulation of peptidase activity
4.73 1.47e-02 GO:0043086 negative regulation of catalytic activity
8.17 1.70e-02 GO:0002252 immune effector process
49.68 1.75e-02 GO:0034374 low-density lipoprotein particle remodeling
8.00 1.94e-02 GO:0019935 cyclic-nucleotide-mediated signaling
13.58 2.32e-02 GO:0072376 protein activation cascade
165.57 2.55e-02 GO:0010949 negative regulation of intestinal phytosterol absorption
165.57 2.55e-02 GO:0045796 negative regulation of intestinal cholesterol absorption
4.43 2.68e-02 GO:0050776 regulation of immune response
6.23 3.10e-02 GO:0002253 activation of immune response
41.40 3.19e-02 GO:0043252 sodium-independent organic anion transport
2.37 3.33e-02 GO:0048583 regulation of response to stimulus
9.21 3.40e-02 GO:0019933 cAMP-mediated signaling
12.55 3.41e-02 GO:0055088 lipid homeostasis
2.20 3.58e-02 GO:0042221 response to chemical stimulus
2.73 3.76e-02 GO:0051239 regulation of multicellular organismal process
18.93 4.00e-02 GO:0002455 humoral immune response mediated by circulating immunoglobulin
1.49 4.07e-02 GO:0050789 regulation of biological process
1.79 4.18e-02 GO:0051716 cellular response to stimulus

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
3.22 3.55e-09 GO:0005576 extracellular region
3.94 1.29e-06 GO:0044421 extracellular region part
4.45 1.87e-06 GO:0005615 extracellular space
22.30 2.99e-06 GO:0031983 vesicle lumen
21.14 4.33e-05 GO:0031093 platelet alpha granule lumen
20.70 4.93e-05 GO:0034774 secretory granule lumen
19.88 6.32e-05 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
17.44 1.40e-04 GO:0031091 platelet alpha granule
1.94 1.51e-04 GO:0005886 plasma membrane
1.92 2.30e-04 GO:0071944 cell periphery
70.96 8.75e-04 GO:0005577 fibrinogen complex
2.12 1.65e-02 GO:0044459 plasma membrane part
2.72 1.72e-02 GO:0000267 cell fraction
3.04 2.32e-02 GO:0005624 membrane fraction
5.80 2.47e-02 GO:0030141 stored secretory granule
2.94 3.22e-02 GO:0005626 insoluble fraction

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
60.21 6.30e-05 GO:0017127 cholesterol transporter activity
50.95 1.35e-04 GO:0015248 sterol transporter activity
5.45 3.14e-04 GO:0030246 carbohydrate binding
9.02 4.65e-04 GO:0005539 glycosaminoglycan binding
10.45 7.54e-04 GO:0008201 heparin binding
8.34 8.34e-04 GO:0001871 pattern binding
8.34 8.34e-04 GO:0030247 polysaccharide binding
11.43 2.22e-03 GO:0004867 serine-type endopeptidase inhibitor activity
13.36 5.62e-03 GO:0005319 lipid transporter activity
110.38 1.71e-02 GO:0004873 asialoglycoprotein receptor activity
31.05 1.78e-02 GO:0015125 bile acid transmembrane transporter activity
31.05 1.78e-02 GO:0070325 lipoprotein particle receptor binding
29.23 2.16e-02 GO:0043499 eukaryotic cell surface binding
15.06 2.22e-02 GO:0043498 cell surface binding
6.81 4.01e-02 GO:0004866 endopeptidase inhibitor activity
6.55 4.98e-02 GO:0061135 endopeptidase regulator activity